Fatores associados à mortalidade de pessoas vivendo com HIV/AIDS em um serviço de atenção especializada no Rio Grande do Sul: um estudo caso-controle

Abstract

OBJECTIVE: To analyze factors associated with the mortality of People Living with HIV/AIDS (PLWHA) in a specialized care service in the city of Porto Alegre/RS, Brazil. METHODS: case-control study in which sociodemographic, care/behavioral, clinical and treatment variables were investigated. Cases were selected among PLWHA who were diagnosed, linked, and died between the years 2013 and 2018. Controls were PLWHA without the outcome. Fifty-three cases and 212 controls were included, totaling 265 sample units. Conditional Logistic Regression was performed to estimate the Gross and Adjusted Odds Ratios. A conceptual block model was considered for the multivariate analysis. RESULTS: In addition to the mean age of 48 years and life expectancy of 2.7 years after diagnosis, PLWHA diagnosed in hospital (OR= 4.07; 95%CI 1.34 - 12.35) with TB-HIV co-infection (OR= 8.77; 95%CI 1.87 - 41.01), with late diagnosis (OR=8.66; 95%CI 2.96 - 25.32), not retained in the health service (OR= 3.11; 95%CI 1.22 - 7.88) and without adherence to treatment (OR = 3.38; 95% CI 1.17 - 9.71) were more likely to die. CONCLUSION: In the period between diagnosis and death in the years 2013 to 2018, care, clinical and treatment events, such as late diagnosis and non-retention in the health service, had an impact on the chances of death of PLWHA.